CD11c Antibody (PE/Cy7)

• Catalog Number: orb1993552
• Category: Antibodies
• Description: CD11c (p150, alphaX integrin subunit) forms complex with CD18 (beta2 integrin subunit) and is expressed mainly on tissue macrophages and dendritic cells. CD11c binds to complement fragment iC3b, fibrinogen, VCAM-1 and ICAM-2 or e.g. CD90. Like other beta2 integrins, CD11c/CD18 plays roles in cell migration and phagocytosis. Moreover, interaction of CD11c/CD18 with plasminogen regulates plasmin activities, and interaction with heparin counteracts binding of iC3b.
• Clonality: Monoclonal
• Clone Number: BU15
• Tested applications: FC
• Reactivity: Human, Monkey
• Isotype: Mouse IgG1
• Immunogen: Dendritic cells of synovial fluid
• Conjugation: PE/Cy7
• Target: CD11c
• Entrez: 3687
• UniProt ID: P20702
• Storage: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
• Buffer/Preservatives: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
• Alternative names: Integrin alpha X, ITGAX, SLEB6
• Note: For research use only
• Application notes: Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
• Expiration Date: 12 months from date of receipt.