CD107b antibody (APC)

• Catalog Number: orb154455
• Category: Antibodies
• Description: Mouse monoclonal antibody conjugated to APC which recognizes CD107b that is also known as LAMP2, is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. LAMP2 is expressed in the membranes of intracellular granules that contain effector molecules such as perforin, granzymes, eicosanoids, and histamine. It may function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion.
• Clonality: Monoclonal
• Clone Number: H4B4
• Tested applications: FC
• Reactivity: Human
• Isotype: Mouse IgG1 kappa
• Immunogen: Human PBMC
• Dilution range: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. Intracellular and extracellular staining.
• Purity: Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
• Conjugation: APC
• Target: CD107b
• Entrez: 3920
• UniProt ID: P13473
• Storage: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
• Buffer/Preservatives: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
• Alternative names: Anti-LAMP-2 antibody, anti-LAMPB antibody
• Note: For research use only
• Application notes: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. Intracellular and extracellular staining.
• Expiration Date: 12 months from date of receipt.

Flow cytometry analysis (surface staining) of IgE-stimulated human peripheral blood with anti-CD107b (H4B4) APC.