CD107a Antibody (Pacific Blue)

• Catalog Number: orb1993671
• Category: Antibodies
• Description: CD107a (lysosome-associated membrane protein-1, LAMP-1), together with LAMP-2, is a major constituent of lysosomal membrane, 1-2% of total CD107a is found also on the plasma membrane. The LAMP proteins are involved in lysosome biogenesis and are required for fusion of lysosomes with phagosomes. Increased CD107a immunoreactivity is observed in neurones, and in glial cells surrounding senile plaques in Alzheimers disease cases and is localized mainly in medullary epithelial cells, single macrophages and lymphocytes in acute thymic involution. CD107a is a good marker of mast cell activation.
• Clonality: Monoclonal
• Clone Number: H4A3
• Tested applications: FC
• Reactivity: Human, Mouse, Primate
• Isotype: Mouse IgG1 kappa
• Immunogen: Human PBMC
• Conjugation: Pacific Blue
• Target: CD107a
• Entrez: 3916
• UniProt ID: P11279
• Storage: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
• Buffer/Preservatives: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
• Alternative names: LAMP-1, LAMPA
• Note: For research use only
• Application notes: Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests. Intracellular and extracellular staining.
• Expiration Date: 12 months from date of receipt.