Canine GITR / TNFRSF18 Protein

Catalog Number: orb570276

Catalog Number	orb570276
Category	Proteins
Description	Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.
Reactivity	Canine
Tag	C-10×His
Form/Appearance	Powder
Purity	90%
Conjugation	Unconjugated
MW	15.8 kDa
Target	GITR
Protein Sequence	NP_001177673.1
Source	Canine GITR, His Tag (orb570276) is expressed from human 293 cells (HEK293). It contains AA Gly 23 - Pro 154 (Accession # D7F619-1).
Expression System	HEK293
Expression Region	Gly 23 - Pro 154
Endotoxins	1.0 EU per μg
NCBI	NP_001177673.1
Storage	-20℃
Buffer/Preservatives	PBS, pH7.4
Alternative names	AITR,GITR,TNFRSF18,CD357 Read more...
Note	For research use only
Application notes	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 15.8 kDa. The protein migrates as 20-25 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Expiration Date	6 months from date of receipt.