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Calmegin Protein, Human, Recombinant (His)
Catalog Number: orb1961634
| Catalog Number | orb1961634 |
|---|---|
| Category | Proteins |
| Description | Calmegin (CLGN) is a member of the calreticulin family. Calmegin is a testis-specific endoplasmic reticulum chaperone protein. The functions during spermatogenesis as a chaperone for a range of client proteins that is important for sperm adhesion onto the egg zona pellucida and for subsequent penetration of the zona pellucida. It is required for normal male fertility, normal sperm migration from the uterus into the oviduct. Calmegin binds calcium ions and interacts with PDILT. Calmegin may play a role in spermatogeneisis and infertility. |
| Tag | C-6xHis |
| Purity | 98.00% |
| Protein Sequence | Glu20-Trp471 |
| UniProt ID | O14967 |
| MW | 60 KDa (reducing condition) |
| Application notes | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Expression System | HEK293 Cells |
| Biological Origin | Human |
| Biological Activity | Calmegin (CLGN) is a member of the calreticulin family. Calmegin is a testis-specific endoplasmic reticulum chaperone protein. The functions during spermatogenesis as a chaperone for a range of client proteins that is important for sperm adhesion onto the egg zona pellucida and for subsequent penetration of the zona pellucida. It is required for normal male fertility, normal sperm migration from the uterus into the oviduct. Calmegin binds calcium ions and interacts with PDILT. Calmegin may play a role in spermatogeneisis and infertility. |
| Expression Region | Glu20-Trp471 |
| Storage | -20°C |
| Note | For research use only |
