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Catalog Number | orb1308857 |
---|---|
Category | Small Molecules |
Description | BPK-29 hydrochloride |
CAS Number | 2444815-73-8 |
Purity | 99.06% |
MW | 506.46 |
SMILES | Cl.ClCC(=O)N(Cc1ccccc1)C1CCCN(CC1)C(=O)c1ccc(cc1)N1CCOCC1 |
Formula | C26H33Cl2N3O3 |
Biological Activity | BPK-29 hydrochloride is a specific ligand that disrupts the atypical orphan nuclear receptor NR0B1-protein interactions by covalently modifying C274. It impairs the anchorage-independent growth of KEAP1-mutant cancer cells. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |