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Catalog Number | orb1306034 |
---|---|
Category | Small Molecules |
Description | BMS-P5 free base |
CAS Number | 1550371-22-6 |
Purity | 99.96% |
MW | 472.58 |
SMILES | COc1cc(cc2nc(-c3cc4cccnc4n3CC3CC3)n(C)c12)C(=O)N1C[C@H](N)CC[C@@H]1C |
Formula | C27H32N6O2 |
Biological Activity | BMS-P5 free base is a specific and orally active peptidylarginine deiminase 4 (PAD4) inhibitor. BMS-P5 Blocks Formation of Neutrophil Extracellular Traps and Delays Progression of Multiple Myeloma. Administration of BMS-P5 to multiple myeloma-bearing mice delays appearance of symptoms and disease progression Targeting PAD4 may be beneficial for treatment of multiple myeloma. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |