BMS-754807

Catalog Number: orb322221

Catalog Number	orb322221
Category	Small Molecules
Description	BMS-754807 is an inhibitor of the insulin receptor (InsR) and IGF-1R that exhibits anticancer chemotherapeutic activity. BMS-754807 enhances the efficacy of other co-administered chemotherapeutics, decreasing levels of activated Akt, increasing cleavage of PARP and caspase 3, and inhibiting proliferation in pancreatic ductal adenocarcinoma cells and breast cancer cells in vitro and growth of tumor xenografts in vivo.
CAS Number	1001350-96-4
Purity	≥99%
MW	461.51
SMILES	C[C@]1(CCCN1c2nc(c3cccn3n2)Nc4cc([nH]n4)C5CC5)C(=O)Nc6ccc(nc6)F
Formula	C₂₃H₂₆FN₉O
Hazard Information	UN Number: Not dangerous goods
Solubility (25°C)	DMSO 92 mg/mL (199.35 mM) Ethanol 92 mg/mL (199.35 mM) Water Insoluble
Storage	Storage Temp: -20°C
Alternative names	BMS754807 Read more...
Note	For research use only
Expiration Date	12 months from date of receipt.

Chemical structure of BMS-754807

Item 1 of 1
BMS754807 [orb146136]
CAS Number:
[1001350-96-4]
MW:
461.4948
Formula:
C₂₃H₂₄FN₉O
Sizes Available: 100 mg, 250 mg, 1 g, 10 mM * 1 mL in DMSO
BMS-754807 [orb1101928]
Purity:
> 98%
CAS Number:
[1001350-96-4]
MW:
461.49
Formula:
C₂₃H₂₄FN₉O
Sizes Available: 10 mg
BMS-754807 [orb1227184]
Purity:
> 98% (HPLC)
CAS Number:
1001350-96-4
Sizes Available: 100 mg, 50 mg, 25 mg, 10 mg, 5 mg, 2 mg, 1 g, 500 mg, 200 mg
BMS-754807 [orb1305620]
Purity:
98.86%
CAS Number:
1001350-96-4
MW:
461.49
Formula:
C₂₃H₂₄FN₉O
Sizes Available: 5 mg, 10 mg, 100 mg, 50 mg, 25 mg, 2 mg, 1 mg
BMS-754807 [orb1902428]
CAS Number:
1001350-96-4
Sizes Available: 10mM x 1 ml in DMSO