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BMS-1166 hydrochloride

BMS-1166 hydrochloride

Catalog Number: orb1707540

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Catalog Numberorb1707540
CategorySmall Molecules
DescriptionBMS-1166 hydrochloride
CAS Number2113650-05-6
Purity98%
MW677.57
SMILESCl.Cc1c(COc2cc(OCc3cccc(c3)C#N)c(CN3C[C@H](O)C[C@@H]3C(O)=O)cc2Cl)cccc1-c1ccc2OCCOc2c1
FormulaC36H34Cl2N2O7
Biological ActivityMotixafortide (BKT140 4-fluorobenzoyl) is an antagonist of CXCR4 (IC50: 1 nM). BMS-1166 hydrochloride is an inhibitor of PD-1/PD-L1 interaction (IC50: 1.4 nM). BMS-1166 rivalries the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation.
Storage-20°C
NoteFor research use only
Expiration Date12 months from date of receipt.
  • BMS-1166 hydrochloride [orb1089574]

    [2113650-05-6]

    677.57

    C36H34Cl2N2O7

    1 ml x 10 mm (in DMSO), 100 mg, 1 g, 250 mg