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Catalog Number | orb1956273 |
---|---|
Category | Small Molecules |
Description | BMF Protein, Human, Recombinant (His) |
Purity | 98.00% |
MW | Approxiamtely 22.3 kDa |
Biological Activity | BMF(Bcl2 modifying factor) belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. BMF contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. BMF is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis. Alternatively spliced transcript variants encoding different isoforms have been identified. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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