BLU-667 (Pralsetinib)

• Catalog Number: orb573124
• Category: Small Molecules
• Description: BLU-667 (Pralsetinib) is a highly potent, selective, next generation RET inhibitor with IC50 of 0.3-0.4 nM for WT RET, RET mutants V804L, V804M, M918T and CCDC6-RET fusion.
• CAS Number: [2097132-94-8]
• MW: 533.6124
• SMILES: O=C([C@@]1(OC)CC[C@@H](C2=NC(NC3=NNC(C)=C3)=CC(C)=N2)CC1)N[C@H](C4=CC=C(N5N=CC(F)=C5)N=C4)C
• Formula: C₂₇H₃₂FN₉O₂
• Note: For research use only
• Expiration Date: 12 months from date of receipt.