BKM120 (NVP-BKM120, Buparlisib)

• Catalog Number: orb146274
• Category: Small Molecules
• Description: BKM120 is a selective PI3K inhibitor of p110α/β/δ/γ with IC50 of 52 nM/166 nM/116 nM/262 nM, respectively. Reduced potency against VPS34, mTOR, DNAPK, with little activity to PI4Kβ.
• CAS Number: [944396-07-0]
• MW: 410.3936
• SMILES: FC(C1=C([H])C(N([H])[H])=NC([H])=C1C1=C([H])C(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])(F)F
• Formula: C₁₈H₂₁F₃N₆O₂
• Note: For research use only
• Expiration Date: 12 months from date of receipt.