Biotinylated Human IL-1RL1 / ST2 Protein

• Catalog Number: orb1184775
• Category: Proteins
• Description: Interleukin 1 receptor-like 1 (IL1RL1) is also known as ST2, DER4, FIT-1, IL33R, ST2L, ST2V, which belongs to the interleukin-1 receptor family. IL1RL1 contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. IL1RL1 is receptor for interleukin-33 (IL-33), its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. IL1RL1 possibly involved in helper T-cell function. IL1RL1 can interact with MYD88, IRAK1, IRAK4, and TRAF6.
• Reactivity: Human
• Tag: C-Fc & C-Avi
• Form/Appearance: Powder
• Purity: 95%
• Conjugation: Biotin
• MW: 62.5 kDa
• Target: IL-1RL1
• Source: Biotinylated Human IL-1RL1, Fc, (orb1184775) is expressed from human 293 cells (HEK293). It contains AA Lys 19 - Pro 323 (Accession # Q01638-1).
• Expression System: HEK293
• Biological Activity: Immobilized Human IL-33 Protein, His Tag, premium grade at 5 μg/mL (100 μL/well) can bind Biotinylated Human IL-1RL1, Fc, with a linear range of 0.6-10 ng/mL (QC tested).
• Expression Region: Lys 19 - Pro 323
• Endotoxins: 1.0 EU per μg
• Storage: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
• Buffer/Preservatives: 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
• Alternative names: IL1RL1,DER4,FIT-1,IL33R,ST2,ST2L,ST2V,T1
• Note: For research use only
• Application notes: This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (). The protein has a calculated MW of 62.5 kDa. The protein migrates as 80-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expiration Date: 6 months from date of receipt.

Immobilized Human IL-33 Protein, His Tag, premium grade (Cat. No. orb612145) at 5 μg/mL (100 μL/well) can bind Biotinylated Human IL-1RL1, Fc, Avitag (Cat. No. orb1184775) with a linear range of 0.6-10 ng/mL (QC tested).