Biotinylated Human IL-17 RC Protein

• Catalog Number: orb1291791
• Category: Proteins
• Description: Interleukin-17 receptor C (IL-17 RC), also known as IL17Rhom, IL-17RL, is the receptor for IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RA. IL-17A activity is inhibited by IL-17RA, IL-17F is inhibited by IL-17RC, and a combination of soluble IL-17RA/IL-17RC receptors is required for inhibition of the IL-17F/IL-17A activity. Furthermore, activation of IL17RC can lead to the induction of expression of inflammatory chemokines and cytokines such as CXCL1.
• Reactivity: Human
• Tag: C-Fc & C-Avi
• Form/Appearance: Powder
• Purity: 95%
• Conjugation: Biotin
• MW: 77.6 kDa
• Target: IL-17 RC
• Source: Biotinylated Human IL-17 RC, Fc, (orb1291791) is expressed from human 293 cells (HEK293). It contains AA Leu 21 - His 465 (Accession # Q8NAC3-2).
• Expression System: HEK293
• Biological Activity: Immobilized Human IL17A, Tag Free at 5 μg/mL (100 μL/well) can bind Biotinylated Human IL-17 RC, Fc, with a linear range of 0.01-0.156 μg/mL (QC tested).
• Expression Region: Leu 21 - His 465
• Endotoxins: 1.0 EU per μg
• NCBI: NP_703190.2
• Storage: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
• Buffer/Preservatives: PBS, pH7.4
• Alternative names: IL-17 RC,IL-17RC,IL17Rhom,IL-17 receptor C,IL-17RL
• Note: For research use only
• Application notes: This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (). The protein has a calculated MW of 77.6 kDa. The protein migrates as 80-110 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expiration Date: 6 months from date of receipt.

Immobilized Human IL17A, Tag Free at 5 μg/mL (100 μL/well) can bind Biotinylated Human IL-17 RC, Fc, Avitag (Cat. No. orb1291791) with a linear range of 0.01-0.156 μg/mL (QC tested).