Biotinylated Human CCL1 / I-309 / C-C motif chemokine 1 Protein

• Catalog Number: orb1184779
• Category: Proteins
• Description: Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. CCL1, a member of the CC subfamily, is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine (C-C motif) receptor 8.
• Reactivity: Human
• Tag: C-10×His & C-Avi
• Form/Appearance: Powder
• Purity: 90%
• Conjugation: Biotin
• MW: 12.1 kDa
• Target: CCL1
• Source: Biotinylated Human CCL1, His, (orb1184779) is expressed from human 293 cells (HEK293). It contains AA Lys 24 - Lys 96 (Accession # P22362-1).
• Expression System: HEK293
• Expression Region: Lys 24 - Lys 96
• Endotoxins: 1.0 EU per μg
• NCBI: NP_002972.1
• Storage: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
• Buffer/Preservatives: PBS, pH7.4
• Alternative names: CCL1,I-309,C-C motif chemokine 1
• Note: For research use only
• Application notes: This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (). The protein has a calculated MW of 12.1 kDa. The protein migrates as 15 kDa and 17-19 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expiration Date: 6 months from date of receipt.