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Catalog Number | orb1960266 |
---|---|
Category | Small Molecules |
Description | BID Protein, Mouse, Recombinant (His) |
Purity | 98.00% |
MW | The protein has a predicted MW of 22.72 kDa same as Tris-Bis PAGE result. |
Biological Activity | Bid, BH3-interacting domain death agonist, was initially cloned based in its ability to interact with both Bcl-2 and Bax. Bid contains only the BH3 domain, which is required for its interaction with the Bcl-2 family proteins and for its pro-death activity. Bid is susceptible to proteolytic cleavage by caspases, calpains, Granzyme B and cathepsins. Bid is important to cell death mediated by these proteases and thus is the sentinel to protease-mediated death signals. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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