BI-847325

• Catalog Number: orb315487
• Category: Small Molecules
• Description: BI-847325 is an orally bioavailable, and selective dual MEK/Aurora kinase inhibitor with IC50 of 3 nM, 25 nM, 15 nM, 25 nM, and 4 nM for Xenopus laevis Aurora B, human Aurora A and Aurora C, as well as human MEK1 and MEK2, respectively. Phase 1.
• CAS Number: [1207293-36-4]
• MW: 464.5582
• SMILES: O([H])C1=C(/C(/C2C([H])=C([H])C([H])=C([H])C=2[H])=N/C2C([H])=C([H])C(=C([H])C=2[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C2C([H])=C([H])C(C#CC(N([H])C([H])([H])C([H])([H])[H])=O)=C([H])C=2N1[H]
• Formula: C₂₉H₂₈N₄O₂
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Chemical structure of BI-847325