BCTC

SKU: orb1300071

Description

BCTC is a highly potent and selective TRPV1 channel antagonist, effectively blocking both capsaicin- and acid-induced activation (IC50 = 35 nM and 6 nM, respectively). This small molecule is a valuable research tool for investigating TRPV1's role in pain, inflammation, and neurogenic conditions in both cellular and animal models.

Research Area

Neuroscience, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 393514-24-4
• MW: 372.89
• Purity: 99.21%
• Formula: C₂₀H₂₅ClN₄O
• SMILES: CC(C)(C)c1ccc(NC(=O)N2CCN(CC2)c2ncccc2Cl)cc1
• Target: TRP/TRPV Channel,CGRP Receptor,IGF-1R
• Solubility: DMSO:50 mg/mL (134.09 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Transient receptor potential channels, TRPChannel, TRPV1, TRPV Channel, TRPVChannel, TRP Channel, inhibit, Inhibitor, BCTC

Compound Identifiers

PubChem CID

9929425