BCL2L2 Antibody

• Catalog Number: orb1733186
• Category: Antibodies
• Description: This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene.
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: 4G12E6
• Tested applications: ELISA, FC, ICC, IHC
• Reactivity: Human
• Isotype: Mouse IgG2a
• Immunogen: Purified recombinant fragment of human BCL2L2 (AA: 6-118) expressed in E. Coli.
• Concentration: 1mg/ml
• Dilution range: IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000; RCM: 1/200 - 1/400; ELISA: 1/10000
• Conjugation: Unconjugated
• MW: 20.7kDa
• Entrez: 599
• Storage: 4°C; -20°C for long term storage. Avoid freeze/thaw cycles.
• Buffer/Preservatives: Purified antibody in PBS with 0.05% sodium azide
• Alternative names: BCLW; BCL-W; PPP1R51; BCL2-L-2
• Note: For research use only
• Expiration Date: 12 months from date of receipt.