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BAY 41-2272
Catalog Number: orb341512
| Catalog Number | orb341512 |
|---|---|
| Category | Small Molecules |
| Description | Activator of soluble guanylyl cyclase (sGC); acts at a nitric oxide (NO)-independent regulatory site in the sGC α1 subunit. Inhibits platelet aggregation (IC50 = 36 nM) and phenylephrine-induced contractions of rabbit aorta (IC50 = 0.30 μM). Also reduces vascular smooth muscle growth through cAMP- and cGMP-dependent PKA and PKG pathways.. For the detailed information of BAY 41-2272, the solubility of BAY 41-2272 in water, the solubility of BAY 41-2272 in DMSO, the solubility of BAY 41-2272 in PBS buffer, the animal experiment (test) of BAY 41-2272, the cell expriment (test) of BAY 41-2272, the in vivo, in vitro and clinical trial test of BAY 41-2272, the EC50, IC50,and affinity,of BAY 41-2272, Please contact DC Chemicals. |
| CAS Number | [256376-24-6] |
| MW | 360.3876 |
| SMILES | FC1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N1C2=C(C([H])=C([H])C([H])=N2)C(C2=NC([H])=C(C(N([H])[H])=N2)C2([H])C([H])([H])C2([H])[H])=N1 |
| Formula | C20H17FN6 |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
Chemical structure of BAY 41-2272
BAY 41-2272 [orb1300478]
99.54%
256376-24-6
360.39
C20H17FN6
50 mg, 100 mg, 2 mg, 5 mg, 10 mg, 25 mg, 1 ml x 10 mm (in DMSO)BAY 41-2272 [orb2655743]
> 98% (HPLC)
256376-24-6
360.4
C20H17FN6
10 mg, 2 mg, 5 mg, 25 mg, 50 mg, 100 mg
