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Catalog Number | orb1961583 |
---|---|
Category | Small Molecules |
Description | BAG2 Protein, Human, Recombinant (His) |
Purity | 98.00% |
MW | 25-30 KDa, reducing conditions |
Biological Activity | BAG Family Molecular Chaperone Regulator 2 (BAG2) is a member of the Bag family whose members compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. BAG2 contains 1 BAG domain and is a important component of the HSC 70/CHIP chaperone-dependent ubiquitin ligase complex. In mammalian cells BAG1, BAG2, and BAG3 bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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