You have no items in your shopping cart.
Cart summary
BAG2 Protein, Human, Recombinant (His)
Catalog Number: orb1961583
| Catalog Number | orb1961583 |
|---|---|
| Category | Proteins |
| Description | BAG Family Molecular Chaperone Regulator 2 (BAG2) is a member of the Bag family whose members compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. BAG2 contains 1 BAG domain and is a important component of the HSC 70/CHIP chaperone-dependent ubiquitin ligase complex. In mammalian cells BAG1, BAG2, and BAG3 bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. |
| Tag | N-6xHis |
| Purity | SDS-PAGE: 95.19%; SEC-HPLC: 97.85% |
| MW | 25-30 KDa (reducing condition) |
| UniProt ID | O95816 |
| Protein Sequence | Met1-Asn211 |
| Expression System | E. coli |
| Biological Origin | Human |
| Biological Activity | BAG Family Molecular Chaperone Regulator 2 (BAG2) is a member of the Bag family whose members compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. BAG2 contains 1 BAG domain and is a important component of the HSC 70/CHIP chaperone-dependent ubiquitin ligase complex. In mammalian cells BAG1, BAG2, and BAG3 bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. |
| Expression Region | Met1-Asn211 |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 6 months from date of receipt. |
