B3GNT2 Protein, Human, Recombinant (hFc)

• Catalog Number: orb1956646
• Category: Small Molecules
• Description: B3GNT2 Protein, Human, Recombinant (hFc)
• Purity: 98.00%
• MW: Approxiamtely 71.2 kDa
• Biological Activity: B3GNT2 belongs to the beta-1,3-N-acetylglucosaminyltransferase family. It is a type II transmembrane protein that prefers the substrate of lacto-N-neotetraose. Alternative splicing produced 2 isoforms of the human protein. B3GNT2 catalyzes the initiation and elongation of poly-N- acetyllactosamine chains. Enzymatic activities of some glycosyltransferases are markedly increased via complex formation with other transferases or cofactor proteins. B3GNT2 and beta3Gn-T8 can form a heterodimer in vitro and that the complex exhibits much higher enzymatic activity than either enzyme alone. It is found that up-regulation of beta3Gn-T8 in differentiated HL-60 cells may increase poly-N-acetyllactosamine chains by activating intrinsic B3GNT2.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.