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Catalog Number | orb401791 |
---|---|
Category | Small Molecules |
Description | AZD5582 is a novel class of dimeric Smac mimetics as potent IAP antagonist; binds potently to the BIR3 domains of cIAP1, cIAP2, and XIAP (IC50 = 15, 21, and 15 nM, respectively). |
CAS Number | [1258392-53-8] |
MW | 1015.2887 |
SMILES | O=C([C@]([H])(C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])N([H])C([C@]([H])(C([H])([H])[H])N([H])C([H])([H])[H])=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(N([H])[C@@]1([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[C@@]1([H])OC([H])([H])C#CC#CC([H])([H])O[C@]1([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[C@]1([H])N([H])C([C@]1([H])C([H])([H])C([H])([H])C([H])([H])N1C([C@]([H])(C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])N([H])C([C@]([H])(C([H])([H])[H])N([H])C([H])([H])[H])=O)=O)=O)=O |
Formula | C58H78N8O8 |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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