AXL antibody (FITC)

• Catalog Number: orb7247
• Category: Antibodies
• Description: The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, the Axl protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors such as vitamin K dependent protein growth arrest specific gene 6. It is involved in the stimulation of cell proliferation. This receptor can also mediate cell aggregation by homophilic binding. Axl is a chronic myelogenous leukemia associated oncogene and also associated with colon cancer and melanoma.The Axl gene is evolutionarily conserved between vertebrate species. This gene has two different alternatively spliced ​​transcript variants (AXL1 and AXL2)
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: IF
• Predicted Reactivity: Canine, Equine, Rabbit, Rat
• Reactivity: Human
• Isotype: IgG
• Immunogen: KLH conjugated synthetic peptide derived from human AXL: 151-250/894
• Concentration: 100 μg (in 100 μl): 1 mg/ml
• Dilution range: IF=1:50-200
• Form/Appearance: Lyophilized or Liquid
• Purity: Affinity purified by Protein A
• Conjugation: FITC
• MW: 95kDa
• Target: AXL
• UniProt ID: P30530
• Storage: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
• Buffer/Preservatives: 0.01M TBS(pH7.4) with 1% rAlbumin, 0.03% Proclin300 and 50% Glycerol.
• Alternative names: anti-AXL antibody, anti-AXL/UFO antibody, anti-Adh
• Note: For research use only
• Expiration Date: 12 months from date of receipt.