ATN-161 TFA

• Catalog Number: orb1910719
• Category: Small Molecules
• Description: ATN-161 is a small peptide antagonist of integrin alpha5beta1 with potential antineoplastic activity. ATN-161 selectively binds to and blocks the receptor for integrin alpha5beta1, thereby preventing integrin alpha5beta1 binding. This receptor blockade may result in inhibition of endothelial cell-cell interactions, endothelial cell-matrix interactions, angiogenesis, and tumor progression. Integrin alpha5beta1 is expressed on endothelial cells and plays a crucial role in endothelial cell adhesion and migration. Note: The Catalog number of ATN-161 TFA salt was changed from 200350B to 206976.
• CAS Number: [904763-27-5]
• MW: 711.667854309082
• SMILES: C(F)(F)(F)C(=O)O.C([C@@H]1CCCN1C(=O)C)(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CS)C(=O)N[C@H](C(=O)N)CC(=O)N)CC1NC=NC=1
• Formula: C₂₅H₃₆F₃N₉O₁₀S
• Note: For research use only
• Expiration Date: 12 months from date of receipt.