ATG3 Antibody

• Catalog Number: orb1729834
• Category: Antibodies
• Description: E2-like enzyme involved in autophagy and mitochondrial homeostasis. Catalyzes the conjugation of ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A) to phosphatidylethanolamine (PE). Catalyzing the conjugation of ATG12 to itself, ATG12 conjugation to ATG3 playing a role in mitochondrial homeostasis but not in autophagy. ATG7 (E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with ATG3.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: ICC, IHC, WB
• Reactivity: Human, Mouse, Rat
• Isotype: Rabbit IgG
• Immunogen: A synthesized peptide derived from human Apg3 (Atg3)
• Dilution range: WB: 1/500-1/1000; IHC: 1/50-1/100; ICC: 1/50-1/200
• Conjugation: Unconjugated
• MW: Calculated MW: 36 kDa; Observed MW: 40 kDa
• Entrez: 64422
• UniProt ID: Q9NT62
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Buffer/Preservatives: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Alternative names: APG3; APG3L; PC3-96; APG3-LIKE
• Note: For research use only
• Expiration Date: 12 months from date of receipt.