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Catalog Number | orb303321 |
---|---|
Category | Antibodies |
Description | Mouse monoclonal antibody to ASyO5 |
Species/Host | Mouse |
Clonality | Monoclonal |
Tested applications | ELISA |
Reactivity | Human |
Isotype | IgG1 |
Immunogen | synthetic peptide derived from human alpha-synuclein Gly111-Tyr125 |
Dilution range | ELISA: 2-4 μg/ml |
Form/Appearance | Lyophilized |
Purity | Immunogen affinity purified serum in PBS pH 7.4. |
Conjugation | Unconjugated |
MW | 14 kDa |
Storage | Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube. |
Note | For research use only |
Application notes | Alpha-synuclein is normally an unstructured soluble protein that can aggregate to form insoluble fibrils in pathological conditions characterized by Lewy bodies, such as Parkinson's disease, dementia with Lewy-bodies, and multiple system atrophy. In analogy to many other amyloid associated disorders, alpha-synuclein may also form oligomeric assemblies. These small and soluble forms have been suggested to exert a stronger tissue damaging effect as compared to the monomeric and fibrillar counterpart. Using a recently developed technique a monoclonal oligomer-specific antibody has been designed. |
Expiration Date | 12 months from date of receipt. |
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