ASIP antibody

• Catalog Number: orb536334
• Category: Antibodies
• Description: In mice, the agouti gene encodes a paracrine signaling molecule that causes hair follicle melanocytes to synthesize pheomelanin, a yellow pigment, instead of the black or brown pigment, eumelanin. Pleiotropic effects of constitutive expression of the mouse gene include adult-onset obesity, increased tumor susceptibility, and premature infertility. This gene is highly similar to the mouse gene and encodes a secreted protein that may (1) affect the quality of hair pigmentation, (2) act as a pharmacological antagonist of alpha-melanocyte-stimulating hormone, (3) play a role in neuroendocrine aspects of melanocortin action, and (4) have a functional role in regulating lipid metabolism in adipocytes.
• Clonality: Polyclonal
• Tested applications: ICC, IF
• Reactivity: Human
• Isotype: IgG
• Immunogen: Recombinant fusion protein of human ASIP(NP_001663.2).
• Dilution range: IF: 1:50-1:200
• Conjugation: Unconjugated
• MW: 14kDa
• UniProt ID: P42127
• Storage: Store at -20°C. Avoid freeze / thaw cycles.
• Buffer/Preservatives: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
• Alternative names: ASIP, AGSW, AGTI, AGTIL, ASP, SHEP9
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Immunofluorescence analysis of HeLa cells using ASIP antibody.