ARRB1 antibody

• Catalog Number: orb67279
• Category: Antibodies
• Description: Rabbit polyclonal to ARRB1.Beta-arrestin-1 (ARRB1) is a cytosolic protein that belongs to the arrestin family. Beta arrestinsfunction in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediatingboth receptor desensitization and resensitization processes. It is involved in IL8-mediated granulerelease in neutrophils. Beta-arrestin-1 acts as a cofactor in the beta-adrenergic receptor kinase(BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, itis expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system isbelieved to play a major role in regulating receptor-mediated immune functions.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: WB
• Reactivity: Human
• Immunogen: N-terminal region of human ARRB1
• Dilution range: WB:1:1000-1:5000
• Purity: Affinity purification
• Conjugation: Unconjugated
• MW: 47
• UniProt ID: P49407
• Storage: -20°C
• Buffer/Preservatives: 0.01% NaN3
• Alternative names: anti-ARRB1 antibody,anti-Betaarrestin1 antibody,an
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Western blot of total cell extracts from human MCF7 using ARRB1 antibody