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AR-V7 Antibody / Androgen Receptor
Catalog Number: orb2636262
| Catalog Number | orb2636262 |
|---|---|
| Category | Antibodies |
| Description | Androgen Receptor is a member of the superfamily of ligand responsive transcription regulators. The androgen receptor functions in the nucleus where it is believed to act as a transcriptional regulator mediating the action of male sex hormones. The androgen receptor has wide distribution and can be demonstrated by immunohistochemistry in several tissues including prostate, skin, and oral mucosa. Androgen receptor has been reported in a diverse range of human tumors including osteosarcoma, and in prostatic carcinoma androgen receptor expression may be of clinical relevance. |
| Species/Host | Rabbit |
| Clonality | Recombinant |
| Clone Number | DHTR/9119R |
| Tested applications | IHC-P |
| Reactivity | Human |
| Isotype | Rabbit IgG, kappa |
| Immunogen | A recombinant fragment (within amino acids 1-200) of human Androgen Receptor protein was used as the immunogen for the recombinant AR-V7 antibody. |
| Antibody Type | Primary Antibody |
| Dilution range | Immunohistochemistry (FFPE): 1-2ug/ml |
| Conjugation | Unconjugated |
| Formula | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide |
| Hazard Information | This recombinant AR-V7 antibody is available for research use only. |
| UniProt ID | P10275 |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Note | For research use only |
| Application notes | Optimal dilution of the recombinant AR-V7 antibody should be determined by the researcher. |
| Expiration Date | 12 months from date of receipt. |
IHC staining of FFPE human prostate carcinoma tissue with recombinant AR-V7 antibody (clone DHTR/9119R). Inset: PBS used in place of primary Ab (secondary Ab negative control). HIER: boil tissue sections in pH9 10 mM Tris with 1 mM EDTA for 20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free recombinant AR-V7 antibody (clone DHTR/9119R) as confirmation of integrity and purity.
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