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APTO-253
Catalog Number: orb1309990
| Catalog Number | orb1309990 |
|---|---|
| Category | Small Molecules |
| Description | APTO-253 |
| CAS Number | 916151-99-0 |
| Purity | 99.43% |
| MW | 367.38 |
| SMILES | CC1=C(C=2NC=3C(=C4C(=C5C3C=CC=N5)N=CC=C4)N2)C=6C(N1)=CC=C(F)C6 |
| Formula | C22H14FN5 |
| Biological Activity | APTO-253 (LOR-253) inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells. APTO-253 mediates anticancer activity through the induction of the KLF4 tumor suppressor. |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
- Item 1 of 1
APTO-253 [orb1219529]
> 98% (HPLC)
916151-99-0
5 mg, 2 mg, 1 g, 500 mg, 200 mg, 25 mg, 100 mg, 50 mg, 10 mg
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