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Catalog Number | orb1961545 |
---|---|
Category | Small Molecules |
Description | Apolipoprotein E/APOE3 Protein, Human, Recombinant (His) |
Purity | 98.00% |
MW | 39 KDa, reducing conditions |
Biological Activity | ApoE, a glycoprotein, is a structural component of very low density lipoprotein (vLDL) synthesized by the liver and intestinally synthesized chylomicrons . ApoE is also a constituent of a subclass of high density of lipoproteins (HDL) involved in cholesterol transport .ApoE mediates high affinity binding of chylomicrons and vLDL particles to the LDL receptor, allowing for specific uptake of these particles by the liver, preventing the accumulation of cholesterol rich particles in the plasma .Apolipoprotein E combines with fats (lipids) in the body to form molecules called lipoproteins and Apolipoprotein E is a major component of a specific type of lipoprotein called very low-density lipoproteins (VLDLs). |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
98.00% | |
Approxiamtely 51.3 kDa |
98.00% | |
Approxiamtely 51.3 kDa |
98.00% | |
The protein has a predicted MW of 35.3 kDa. Due to glycosylation, the protein migrates to 35-45 kDa based on Tris-Bis PAGE result. |
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