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Catalog Number | orb1960141 |
---|---|
Category | Small Molecules |
Description | Apolipoprotein E/APOE3 Protein, Human, Recombinant (hFc) |
Purity | 98.00% |
MW | The protein has a predicted MW of 59.76 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result. |
Biological Activity | Apolipoprotein E (apoE) is a lipid carrier in both the peripheral and the central nervous systems. Lipid-loaded apoE lipoprotein particles bind to several cell surface receptors to support membrane homeostasis and injury repair in the brain. Considering prevalence and relative risk magnitude, the ε4 allele of the APOE gene is the strongest genetic risk factor for late-onset Alzheimer's disease (AD). |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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