You have no items in your shopping cart.
Cart summary
Apolipoprotein A-IV/APOA4 Protein, Human, Recombinant (His)
Catalog Number: orb1955420
| Catalog Number | orb1955420 |
|---|---|
| Category | Proteins |
| Description | Apolipoprotein is genetically associated with the risk of Alzheimer's disease (AD). The APOA1, APOC3, and APOA4 genes are closely linked and located on human chromosome 11. There was a decreased trend for levels of APOA1, APOC3, and APOA4 in AD patients. CONCLUSION: Low levels of APOA1, APOC3, and APOA4 are associated with risk of AD. APOA1, APOC3, and APOA4 should be developed as combined drugs for the therapy of AD. SNP(single nucleotide polymorphisms)in APOA1and APOA4 genes influences atherogenic characteristics of LDL particles in response to diet. |
| Tag | C-His |
| Purity | 99.00% |
| UniProt ID | P06727 |
| MW | 44.8 kDa (predicted) |
| Application notes | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
| Expression System | HEK293 Cells |
| Biological Origin | Human |
| Biological Activity | Apolipoprotein is genetically associated with the risk of Alzheimer's disease (AD). The APOA1, APOC3, and APOA4 genes are closely linked and located on human chromosome 11. There was a decreased trend for levels of APOA1, APOC3, and APOA4 in AD patients. CONCLUSION: Low levels of APOA1, APOC3, and APOA4 are associated with risk of AD. APOA1, APOC3, and APOA4 should be developed as combined drugs for the therapy of AD. SNP(single nucleotide polymorphisms)in APOA1and APOA4 genes influences atherogenic characteristics of LDL particles in response to diet. |
| Expression Region | A DNA sequence encoding the human APOA4 (NP_000473.2) (Met1-Ser396) was expressed with a polyhistidine tag at the C-terminus. Predicted N terminal: Glu 21 |
| Storage | -20°C |
| Note | For research use only |
