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    APOBEC3 gamma antibody

    Catalog Number: orb67157

    DispatchUsually dispatched within 5-10 working days.
    $ 527.00
    Catalog Numberorb67157
    CategoryAntibodies
    DescriptionRabbit polyclonal to APOBEC3 gamma.DNA dC-dU-editing enzyme APOBEC-3G (APOBEC3G) belongs to the cytidine and deoxycytidylatedeaminase family. It is a DNA deaminase (cytidine deaminase) that mediates a form of innateresistance to retroviral infections (at least to HIV-1 infection) by triggering G-to-A hypermutation in thenewly synthesized viral DNA. The inhibition of viral replication is either due to the degradation of theminus strand before its integration or to the lethality of the hypermutations. APOBEC3G also inhibitsthe infectivity of retroviral particles only distantly related to HIV-1, such as the simianimmunodeficiency virus (SIV), the equine infectious anemia virus (EIAV) and the murine leukemiavirus (MLV).
    Species/HostRabbit
    ClonalityPolyclonal
    Tested applicationsWB
    ReactivityHuman
    ImmunogenN-terminal region of human APOBEC3G
    Dilution rangeWB:1:500-1:1000
    PurityAffinity purification
    ConjugationUnconjugated
    MW46
    UniProt IDQ9HC16
    Storage-20°C
    Buffer/Preservatives0.01% NaN3
    Alternative namesanti-APOBEC3 gamma antibody,anti-DNA dCGreater tha
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    NoteFor research use only
    Expiration Date12 months from date of receipt.
    APOBEC3 gamma antibody

    Western blot of total cell extracts from human Jurkat using APOBEC3 gamma antibody

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