Apitolisib(GDC-0980)

• Catalog Number: orb154688
• Category: Small Molecules
• Description: GDC-0980 (RG7422) is a potent, class I PI3K inhibitor for PI3Kα/β/δ/γ with IC50 of 5 nM/27 nM/7 nM/14 nM, respectively. Also a mTOR inhibitor with Ki of 17 nM, and highly selective versus others PIKK family kinases.
• CAS Number: [1032754-93-0]
• MW: 498.6011
• SMILES: S1C2C(=NC(C3=C([H])N=C(N([H])[H])N=C3[H])=NC=2C(C([H])([H])[H])=C1C([H])([H])N1C([H])([H])C([H])([H])N(C([C@]([H])(C([H])([H])[H])O[H])=O)C([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
• Formula: C₂₃H₃₀N₈O₃S
• Note: For research use only
• Expiration Date: 12 months from date of receipt.