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AP4dT
Catalog Number: orb64074
| Catalog Number | orb64074 |
|---|---|
| Category | Small Molecules |
| Description | AP4dT |
| Form/Appearance | solution in water; Color: colorless to slightly yellow; pH: 7.5 ± 0.5 |
| Concentration | 10 mM-11 mM |
| Purity | ≥ 95% (HPLC) |
| MW | Theoretical MW: 811.38 g/mol (free acid); Detected MW: 811.04 g/mol (free acid) |
| Application notes | Spectroscopic Propertie: λmax 262 nm, ε 22.3 L mmol-1 cm-1 (Tris-HCl, pH 7.5). |
| CAS Number | 13457-68-6 |
| Formula | C20H29N7O20P4 |
| SMILES | O=P(OP(=O)(OP(=O)(OCC1O[C@@H](n2c(=O)[nH]c(=O)c(C)c2)C[C@@H]1O)O)O)(OP(=O)(OC[C@@H]1[C@H]([C@H]([C@@H](O1)n1c2c(nc1)c(ncn2)N)O)O)O)O |
| Storage | store at -20 °C |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
For example, if the dosage of your experiment is 10mg/kg, the weight of each animal is 50g, and the volume of the dosing is 100μL, then the working solution concentration of your experiment is 5mg/mL. If the formula you used is 5% DMSO+ 30% PEG300+ 5% Tween 80 + 60% Saline/PBS/ddH2O, the preparation method is as follows:
Mother liquor preparation method: 5mg of drug dissolved in 100μL DMSO (mother liquor concentration is 50mg/mL). Preparation method of in vivo formulation: For 1mL of working solution preparation, take 50μL of DMSO mother liquor, add 300 μL of PEG300 to mix well and clarify, then add 50μL of Tween-80 to mix well and clarify, and finally add 600μL of Saline/PBS/ddH2O to mix well and clarify.Note:
- For Reference Only. Please choose the appropriate dissolution protocol according to your experimental animal and administration method.
- We suggest that in cell experiments, the final concentration of DMSO is not more than 0.1%, in animal experiments, for healthy mice, the final concentration of DMSO is not more than 10%; For nude or frail mice, the final concentration of DMSO is not more than 2%.
