CD161 Antibody

SKU: orb154387

Description

Mouse monoclonal antibody to CD161 which is expressed in a subset of NK cells predominantly in intestinal epithelium and liver that participates in inhibitory role on natural killer (NK) cells cytotoxicity and also plays role as a lectin that binds to the terminal carbohydrate Gal-alpha(1,3)Gal epitope as well as to the N-acetyllactosamine epitope.

Images & Validation

• Tested Applications: FC, IHC-Fr, IP, RIA, WB
• Reactivity: Rat
• Application Notes:
  Flow cytometry: Recommended dilution: 1-4 μg/ml.

Key Properties

• Antibody Type: Primary Antibody
• Clonality: Monoclonal
• Isotype: Mouse IgG1 kappa
• Clone No.: 10/78
• Immunogen: Splenic cells purified from the LEW rat
• Target: CD161
• Purification: Purified by protein-A affinity chromatography.

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
• Concentration: 1 mg/ml
• Disclaimer: For research use only

Alternative Names

NKRP1A, Klrb

Separation of rat CD161 positive splenocytes (red-filled) from CD161 negative splenocytes (black-dashed) in flow cytometry analysis (surface staining) of rat splenocyte suspension stained using anti-rat CD161 (10/78) purified antibody (concentration in sample 0.5 μg/ml) GAM APC.

Flow cytometry surface staining pattern of rat splenocyte suspension stained using anti-rat CD161 (10/78) purified antibody (concentration in sample 0.5 μg/ml) GAM APC.

Quick Database Links

Gene Symbol

CD161

UniProt

Q0ZUP0

NCBI Gene ID

689817