Anti-ROR1 Reference Antibody (zilovertamab vedotin)

• Catalog Number: orb1818280
• Category: Antibodies
• Description: Recombinant Antibody
• Clonality: Monoclonal
• Isotype: IgG1
• Conjugation: Unconjugated
• Reactivity: Human
• Form/Appearance: Purified monoclonal antibody supplied in PBS, pH 6.0, without preservative.This antibody is purified through a protein A column.
• Concentration: 1mg/ml
• Protein Sequence: ROR1
• UniProt ID: Q01973
• MW: 145.12
• Tested applications: ELISA, FC
• Antibody Type: Primary Antibody
• Expression System: CHO Cell
• Endotoxins: < 0.001EU/μg,determined by LAL method.
• Alternative names: Inactive tyrosine-protein kinase transmembrane rec
• Note: For research use only

The purity of Anti-ROR1 Reference Antibody (zilovertamab vedotin) is more than 98.21%, determined by SEC-HPLC.

Immobilized human ROR1 His at 2 µg/mL can bind Anti-ROR1 Reference Antibody (zilovertamab vedotin), EC50=0.002833 µg/mL

zilovertamab vedotin inhibited the tumor growth of MDA-MB-231on NSG mice. The result showed significant anti-tumor effects, with an tumor inhibition rate (TGI) of 96.6% at 10 mpk.

Anti-ROR1 Reference Antibody (zilovertamab vedotin) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%