Anti-Polysialic acid [735]

SKU: orb348875

Description

Mouse monoclonal antibody to Polysialic acid

Research Area

Cancer Biology, Neuroscience, Stem Cell & Developmental Biology

Images & Validation

• Tested Applications: FC, IB, IHC, IP, WB
• Reactivity: Human, Mouse, Rat

Key Properties

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG2a
• Clone No.: 735
• Immunogen: Homopolymers of α2,8-linked sialic acid of Escherichia coli K1.
• Target: Polysialic acid
• Purity: Purified
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: PBS with 0.02% Proclin 300.
• Concentration: 1 mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

PSA; N-CAM; neural cell adhesion molecule; polySA

Immunohistochemical staining of guinea pig brain using anti-polysialic acid antibody orb348916 Formalin fixed guinea pig brain slices were were stained with a orb348916 at 3 µg/ml.

Immunohistochemical staining of rat spinal chord using anti-polysialic acid antibody orb348916 Formalin fixed rat spinal chord slices were were stained with a orb348916 at 3 µg/ml.

Western Blot using anti-polysialic acid antibody. Rat brain lysate was resolved on a 10% SDS PAGE gel and blots probed with orb348916 at 2 µg/ml before being detected by a secondary antibody.

Quick Database Links

Gene Symbol

Polysialic acid

Bitter-Suermann, D. et al. Monoclonal antibodies to polysialic acid reveal epitope sharing between invasive pathogenic bacteria, differentiating cells and tumor cells Immunol Res, 6, 225-237 (1987)

PubMed: 2448401

Reactivity

Mouse