Anti-MOG [M3-8]

• Catalog Number: orb1821648
• Category: Antibodies
• Description: Anti-MOG [M3-8]
• Target: MOG
• Clonality: Monoclonal
• Species/Host: Monkey
• Isotype: Monkey IgG1
• Conjugation: Unconjugated
• Reactivity: Rat
• Concentration: 1 mg/ml
• Buffer/Preservatives: PBS with 0.02% Proclin 300.
• Immunogen: Callithrix jacchus marmosets were used, and experimental allergic encephalomyelitis was induced by the injection of rat MOG (aa1-125) into the marmosettes. The rMOG was expressed in E. coli and purified to homogeneity. The animals were killed 4-70 days after the onset of symptoms of EAE. Bone marrow and spleen cells were obtained from an immunized C. jacchus, the RNA extracted with Trizol reagent and rtPCR used to generate cloning inserts containing Fab portions of IgGk. Phage display was then used to select for the MOG-reactive Fab fragments using the pCOMB3H phage display vector, and binding confirmed using an ELISA.
• UniProt ID: Q63348
• Tested applications: Blocking, ELISA, IHC
• Clone Number: M3-8
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Alternative names: Myelin oligodendrocyte glycoprotein; rMOG
• Note: For research use only