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Anti-IL-31Ra Reference Antibody (nemolizumab)

Catalog Number: orb1806167

DispatchUsually dispatched within 5-10 working days
$ 80.00
Catalog Numberorb1806167
CategoryAntibodies
DescriptionAnti-IL-31Ra Reference Antibody is expressed from CHO. The heavy chain type is huIgG2, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.
ClonalityMonoclonal
Tested applicationsELISA, FA, FACS, Kinetics
ReactivityHuman
IsotypeIgG
Purity> 95%
ConjugationUnconjugated
MW145.5 kDa
TargetIL-31Ra
Endotoxins< 1 EU/mg
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Buffer/Preservatives100 mM Pro-Ac 20 mM Arg pH 5.0
NoteFor research use only
Expiration Date12 months from date of receipt.
Anti-IL-31Ra Reference Antibody (nemolizumab)

Anti-IL-31Ra Reference Antibody (nemolizumab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

Anti-IL-31Ra Reference Antibody (nemolizumab)

The purity of Anti-IL-31Ra Reference Antibody (nemolizumab)is more than 100% ;determined by SEC-HPLC.

Anti-IL-31Ra Reference Antibody (nemolizumab)

Immobilized human IL31R His at 2 μg/mL can bind Anti-IL-31Ra Reference Antibody (nemolizumab);EC50=0.0153μg/mL.

Anti-IL-31Ra Reference Antibody (nemolizumab)

Human IL31R HEK293 cells were stained with Anti-IL-31Ra Reference Antibody (nemolizumab) and negative control protein respectively; washed and then followed by PE and analyzed with FACS; EC181=0.307 μg/mL.

Anti-IL-31Ra Reference Antibody (nemolizumab)

Anti-IL-31Ra Reference Antibody (nemolizumab) P-STAT3 Assay was evaluated using Du145. The IC50 was approximately 0.1068 ug/ml.

Anti-IL-31Ra Reference Antibody (nemolizumab)

Anti-IL-31Ra Reference Antibody (nemolizumab) Activation inhibition was evaluated using Hacat. The max induction fold was approximately 1.86.