CD195 Antibody

SKU: orb154409

Description

Mouse monoclonal antibody to CD195 which belongs to the G-protein coupled receptor 1 family. It also known as CCR5. It highly expressed in spleen, thymus. CD195 play a role in the control of granulocytic lineage proliferation or differentiation. It acts as a coreceptor for HIV-1 R5 isolates.

Research Area

Epigenetics, GPCR, Infectious Diseases, Neuroscience, Signaling Pathways

Images & Validation

• Tested Applications: ELISA, FC, ICC, IP, WB
• Reactivity: Human
• Application Notes:
  Western blotting: Do not boil cell lysates prior to SDS-PAGE. Flow cytometry: Recommended dilution: 1-4 µg/ml

Key Properties

• Antibody Type: Primary Antibody
• Clonality: Monoclonal
• Isotype: Mouse IgG1 kappa
• Clone No.: T21/8
• Immunogen: CCR5 peptide (Met1-Lys22) KLH conjugate
• Target: CD195
• Purification: Purified by protein-A affinity chromatography.
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
• Concentration: 1 mg/ml
• Disclaimer: For research use only

Alternative Names

CKR5, CCR5, CCCKR5, CMKBR5, IDDM22, CC-CKR-5

Separation of human CD195 positive lymphocytes (red-filled) from CD195 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD195 (T21/8) purified antibody (concentration in sample 3 μg/ml) GAM APC.

Flow cytometry surface staining pattern of human peripheral blood stained using anti-human CD195 (T21/8) purified antibody (concentration in sample 3 μg/ml) GAM APC.

Quick Database Links

Gene Symbol

CD195

UniProt

P51681

NCBI Gene ID

1234