CD195 Antibody (PE)

• Catalog Number: orb154530
• Category: Antibodies
• Description: Mouse monoclonal antibody conjugated to PE which recognizes CD195 that belongs to the G-protein coupled receptor 1 family. It also known as CCR5. It highly expressed in spleen, thymus. CD195 play a role in the control of granulocytic lineage proliferation or differentiation. It acts as a coreceptor for HIV-1 R5 isolates.
• Target: CD195
• Clonality: Monoclonal
• Isotype: Mouse IgG1 kappa
• Conjugation: PE
• Reactivity: Human
• Buffer/Preservatives: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
• Purification: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
• Immunogen: CCR5 peptide (Met1-Lys22) KLH conjugate
• UniProt ID: P51681
• Tested applications: FC
• Application notes: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
• Antibody Type: Primary Antibody
• Clone Number: T21/8
• Storage: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
• Alternative names: CKR5, CCR5, CCCKR5, CMKBR5, IDDM22, CC-CKR-5
• Research Area: Epigenetics, GPCR, Infectious Diseases, Neuroscien
• Note: For research use only
• Entrez: 1234
• Expiration Date: 12 months from date of receipt.

Anti-Hu CD195 PE antibody (clone T21/8) specificity verification by flow cytometry. Anti-Hu CD195 PE (concentration in sample 5 μg/ml, red-filled histogram) binds specifically to surface CD195 in transfected cells (upper panel), but not to the parent HEK-293 WT cells (lower panel). Level of non-specific binding was assessed using Mouse IgG1 isotype control PE (MOPC-21) under same conditions (concentration in sample 5 μg/ml, black-dashed histogram).

Anti-Hu CD195 PE antibody (clone T21/8) specificity verification by flow cytometry. Anti-Hu CD195 PE (concentration in sample 5 μg/ml, red-filled histogram) binds specifically to surface CD195 in transfected cells (upper panel), but not to the parent HEK-293 WT cells (lower panel). Level of non-specific binding was assessed using Mouse IgG1 isotype control PE (MOPC-21) under same conditions (concentration in sample 5 μg/ml, black-dashed histogram).

Anti-Hu CD195 PE antibody (clone T21/8) specificity verification by flow cytometry. Anti-Hu CD195 PE (concentration in sample 5 μg/ml, red-filled histogram) binds specifically to surface CD195 in transfected cells (upper panel), but not to the parent HEK-293 WT cells (lower panel). Level of non-specific binding was assessed using Mouse IgG1 isotype control PE (MOPC-21) under same conditions (concentration in sample 5 μg/ml, black-dashed histogram).