HLA-C Antibody

• Catalog Number: orb1088498
• Category: Antibodies
• Description: HLA-C, a member of MHC class I glycoproteins, is one of polymorphysm typing targets, which are important for transplantation. The HLA system plays an important role in the occurrence and outcome of infectious diseases. The structural spike and the nucleocapsid proteins of the novel coronavirus SARS-CoV-2, which causes coronavirus disease 2019 (COVID-19), are reported to contain multiple Class I epitopes with predicted HLA restrictions. Individual HLA genetic variation may help explain different immune responses to a virus across a population. It has been described that HLA-C interacts with human herpesvirus 8 MIR1 protein.
• Target: HLA-C
• Clonality: Monoclonal
• Isotype: Mouse IgG2b
• Conjugation: Unconjugated
• Reactivity: Human, Primate
• Concentration: 1 mg/ml
• Buffer/Preservatives: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
• Purification: Purified by protein-A affinity chromatography.
• Immunogen: Purified MHC class I molecules of tamarin origin
• UniProt ID: P10321
• Tested applications: FC, IP
• Application notes: Flow cytometry: Recommended dilution: 1-4 μg/ml.
• Antibody Type: Primary Antibody
• Clone Number: DT-9
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Alternative names: HLC-C, D6S204, PSORS1, HLA-JY3
• Research Area: Epigenetics, Immunology, Infectious Diseases
• Note: For research use only
• Entrez: 3107

Separation of lymphocytes stained anti-human HLA-C (DT-9) purified antibody (concentration in sample 1.7 μg/ml, GAM APC, red-filled) from lymphocytes unstained by primary antibody (GAM APC, black-dashed) in flow cytometry analysis (surface staining).

Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human HLA-C (DT-9) purified antibody (concentration in sample 1.7 μg/ml, GAM APC).