Anti-CD8 alpha [YTS 105.18]

• Catalog Number: orb348907
• Category: Antibodies
• Description: Rabbit monoclonal antibody to CD8 alpha
• Species/Host: Rat
• Clonality: Monoclonal
• Clone Number: YTS 105.18
• Tested applications: Blocking, FC, IF, IHC-Fr
• Reactivity: Mouse
• Isotype: Rat IgG
• Immunogen: Ly-2-transfected mouse L cells.
• Concentration: 1 mg/ml
• Purity: Purified
• Conjugation: Unconjugated
• Target: CD8 alpha
• UniProt ID: P01731
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: PBS with 0.02% Proclin 300.
• Alternative names: Lyt-2; CD8A Antibody; CD8a molecule Antibody; CD8a
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

References

Satoru Morita ORCID logo et al. Combination CXCR4 and PD1 blockade enhances intratumoral dendritic cell activation and immune responses against hepatocellular carcinoma Cancer Immunology Research,, (2024)

PubMed:

Applications

FC

Qin, S. X. et al. Induction of tolerance in peripheral T cells with monoclonal antibodies Eur J Immunol, 20, 2737-2745 (1990)

PubMed: 1702726

Reactivity

Mouse

Flow-cytometry using anti-CD8a antibody YTS 105.18 Mouse lymphocytes were stained with an isotype control (orb256390, panel A) or the rabbit-chimeric version of YTS 105.18 (orb348907, panel B) at a concentration of 1 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a AF488 conjugated donkey anti-rabbit antibody and cells analysed on a FACSCanto flow-cytometer.