Anti-CD52 [Alemtuzumab (Campath-1H)]

SKU: orb348863

Description

Human monoclonal antibody to CD52

Images & Validation

• Tested Applications: ELISA, FC, IHC-Fr, IHC-P, WB
• Reactivity: Human, Primate

Key Properties

• Host: Human
• Clonality: Monoclonal
• Isotype: IgG1
• Clone No.: Alemtuzumab (Campath-1H)
• Immunogen: Human lymphocytes.
• Target: CD52
• Purity: Purified

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: PBS with 0.02% Proclin 300.
• Concentration: 1 mg/ml
• Disclaimer: For research use only

Alternative Names

CDW52; Cambridge pathology 1 antigen; Epididymal secretory protein E5; Human epididymis-specific protein 5; YTH66.9HL

Immunofluorescence staining of fixed rat thymus tissue with anti-CD52 antibody Campath-1H. Immunofluorescence analysis of fixed rat thymus tissue stained with the chimeric human IgG1 version of Campath-1H (orb348863) at 5 µg/ml followed by a FITC conjugated secondary antibody, showing membrane and cytoplasmic staining of a subset of cells. The nuclear stain is DAPI (blue). Panels show from left-right; orb348863 (FITC), DAPI and merged channels.

Immunofluorescent staining of rat thymus using anti-CD52 antibody. Formaldehyde-fixed rat thymus slices were stained with orb348863 at 5 µg/ml and detected with a FITC-conjugated secondary antibody.

Immunohistochemical staining of human thyroid cancer using anti-CD52 antibody. Formalin fixed human thyroid cancer slices were were stained with a orb348863 at 5 µg/ml.

Immunohistochemical staining of rat epididymis tissue using anti-CD52 antibody Campath-1H. Anti-CD52 staining of formaldehyde fixed paraffin embedded rat epididymis tissue, at 40x magnification. The human IgG1-chimeric version of Campath-1H (orb348863) was used to stain samples at a concentration of 5 µg/ml.

Immunohistochemical staining of rat spleen tissue using anti-CD52 antibody Campath-1H. Anti-CD52 staining of formaldehyde fixed paraffin embedded rat spleen tissue, at 40x magnification. The human IgG1-chimeric version of Campath-1H (orb348863) was used to stain samples at a concentration of 5 µg/ml.

Immunohistochemical staining of rat thymus tissue using anti-CD52 antibody Campath-1H. Anti-CD52 staining of formaldehyde fixed paraffin embedded rat thymus tissue, at 40x magnification. The human IgG1-chimeric version of Campath-1H (orb348863) was used to stain samples at a concentration of 5 µg/ml.

Quick Database Links

Gene Symbol

CD52

UniProt

P31358