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AMCase/CHIA Protein, Human, Recombinant (His)
Catalog Number: orb1959777
| Catalog Number | orb1959777 |
|---|---|
| Category | Small Molecules |
| Description | AMCase/CHIA Protein, Human, Recombinant (His) |
| Purity | 98.00% |
| MW | The protein has a predicted MW of 51.2 kDa. Due to glycosylation, the protein migrates to 55-60 kDa based on Tris-Bis PAGE result. |
| Biological Activity | Acidic mammalian chitinase (AMCase) and chitotriosidase (CHIT-1) are two active chitinases expressed in humans. The chitinase activity of AMCase was found to be causative in allergic inflammation and its expression was found to be induced by interleukin-13. CHIT1-1 is expressed by phagocytic cells and extremely high levels are seen in lysosomal storage diseases. Despite that AMCase expression in the inflammation is under investigation, little is known regarding its regulation during macrophages' full maturation and polarization. |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
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