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AMACR / p504S Antibody (Prostate Cancer Marker)

Catalog Number: orb385979

DispatchUsually dispatched within 5-10 working days
$ 410.00
Catalog Numberorb385979
CategoryAntibodies
DescriptionAMACR, also known as p504S is an enzyme that is involved in bile acid biosynthesis and beta-oxidation of branched-chain fatty acids. It is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands.
Species/HostMouse
ClonalityMonoclonal
Clone NumberAMACR/1723
Tested applicationsIHC-P, WB
ReactivityHuman
IsotypeMouse IgG2b, lambda
ImmunogenA recombinant human protein was used as the immunogen for the AMACR antibody.
Antibody TypePrimary Antibody
Dilution rangeWestern blot: 0.5-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
PurityProtein G affinity chromatography
ConjugationUnconjugated
Formula0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Hazard InformationThis AMACR antibody is available for research use only.
UniProt IDQ9UHK6
StorageStore the AMACR antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Buffer/Preservatives0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin (US sourced) and 0.05% sodium azide
NoteFor research use only
Application notesOptimal dilution of the AMACR antibody should be determined by the researcher.
Expiration Date12 months from date of receipt.
AMACR / p504S Antibody (Prostate Cancer Marker)

Western blot testing of human PC3 cell lysate with AMACR antibody. Predicted molecular weight ~43 kDa.

AMACR / p504S Antibody (Prostate Cancer Marker)

Western blot testing of human kidney lysate with AMACR antibody. Predicted molecular weight ~43 kDa.

AMACR / p504S Antibody (Prostate Cancer Marker)

Western blot testing of human liver lysate with AMACR antibody. Predicted molecular weight ~43 kDa.

AMACR / p504S Antibody (Prostate Cancer Marker)

IHC testing of FFPE human prostate carcinoma with AMACR antibody (clone AMACR/1723). HIER: boil tissue sections in pH9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.

AMACR / p504S Antibody (Prostate Cancer Marker)

SDS-PAGE Analysis of Purified, BSA-Free AMACR Antibody (clone AMACR/1723). Confirmation of Integrity and Purity of the Antibody.

  • AMACR / p504S Antibody (Prostate Cancer Marker) [orb606943]

    IHC-P,  WB

    Human

    Mouse

    Monoclonal

    Unconjugated

    20 μg
  • AMACR / p504S Antibody (Prostate Cancer Marker) [orb2642638]

    IHC-P,  WB

    Human

    Mouse

    Monoclonal

    Unconjugated

    100 μg
  • AMACR / p504S Antibody (Prostate Cancer Marker) [orb2638392]

    IHC-P,  WB

    Human

    Rabbit

    Monoclonal

    Unconjugated

    0.1 ml
  • AMACR / p504S Antibody (Prostate Cancer Marker) [orb316989]

    IHC-P,  WB

    Human

    Rabbit

    Monoclonal

    Unconjugated

    0.5 ml
  • AMACR / p504S Antibody (Prostate Cancer Marker) [orb2639955]

    IHC-P,  WB

    Human

    Mouse

    Monoclonal

    Unconjugated

    100 μg