alpha Smooth Muscle Actin Antibody

• Catalog Number: orb1732685
• Category: Antibodies
• Description: Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Defects in ACTA2 are the cause of aortic aneurysm familial thoracic type 6 (AAT6) [MIM:611788]. They are primarily associated with a characteristic histologic appearance known as 'medial necrosis' or 'Erdheim cystic medial necrosis' in which there is degeneration and fragmentation of elastic fibers, loss of smooth muscle cells, and an accumulation of basophilic ground substance.
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: 1D10
• Tested applications: ICC, IHC, WB
• Reactivity: Human, Mouse, Rat
• Isotype: Mouse IgG1
• Immunogen: Synthetic Peptide of α-SMA
• Concentration: 1mg/ml
• Dilution range: WB: 1/500-1/1000; IHC: 1/50-1/100; ICC: 1/50-1/200
• Conjugation: Unconjugated
• MW: Calculated MW: 42 kDa; Observed MW: 42 kDa
• Entrez: 59
• UniProt ID: P62736
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Buffer/Preservatives: Liquid in PBS containing 50% glycerol, 0.5% rAlbumin and 0.02% sodium azide, pH 7.3.
• Alternative names: ACTA2; ACTSA; ACTVS; GIG46; Actin; aortic smooth m
• Note: For research use only
• Expiration Date: 12 months from date of receipt.